Stickler_Syndrome

Stickler Syndrome Stickler Syndrome Stickler syndrome is a connective tissue disorder, a genetic malfunction in the tissue that connects bones, heart, eyes, and ears. This disorder is associated with problems of vision, hearing, bone and joint , facial and cleft palate, and heart. More serious problems include the gel which fills the eye deteriorating, the retina deteriorating, eyes moving independent of each other, and glaucoma. Any of these serious problems can lead to blindness. The hearing loss suffered by those who are affected will affect either the middle or inner ear. Deafness can result in the extreme cases. Bone and joint problems consist of arthritis, abnormality to ends of long bones, vertebrae abnormality, curvature of the spine, hunchback, joint pain, knock knee, and double jointed. These will tend to worsen with age. Several facial features are common with Sticklers syndrome. Flat cheeks, flat nasal bridge, small upper jaw, pronounced upper lip groove, small ower jaw, and palate abnormalities are syndrome, stickler, problems, joint, chromosome, upper, tissue, small, serious, research, possible, palate, mapped, jaw, heart, hearing, genetic, gene, flat, facial, eyes, exon, disorder, deteriorating, deletion, continuing, common, col2a1, bones, bone, affect, abnormality, 12, worsen, vision