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Lysosomes__Hurlers_Disease

2013-11-13 来源: 类别: 更多范文

Lysosomes/ Hurlers Disease Hurler’s disease could quite possibly be considered as one of the most dangerous types of lysosomal diseases because it is not really detectable until 6 and 24 months after birth. Once the disease is recognized though many times it is too late considering that the individual is already mentally retarded. Children that are affected by this disease have enlarged stomachs because of the fact that their spleens have swollen up. The skeleton also is affected by the lysosomal malfunction, suffers normally have hunched backs and stunted growth. Also the thorax becomes stiff which causes those affected to appear to walk rigidly. As Hurler’s disease progresses the children start to develop similar appearances. Well-marked eyebrows and an abnormal amount of very thick coarse hair are among the most common. Also common to those suffering Hurler’s disease is broad mouths and enlarged tongues. Hearing and vision are also affected because of the build up of fluids in the tissue of the children. Finally because of the mucouspolysaccharide build up the heart is affected which makes the children very susceptible to heart problems. Hurler’s disease is a type of lysosomal disease, which is disease, hurler’s, children, because, affected, causes, build, marrow, lysosomal, heart, common, bone, vision, very, treatment, transplant, tissue, suffers, should, problems, one, months, hearing, enzymes, enlarged, done, cell, caused, work, within, well-marked, walk, usage, until, ultimately
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