Yellow_Fever

Yellow Fever Family : Faviviridae Genus: Flavivirus Size: 40-50nm in diameter Shape: Spherical, nucleocapsid has icosahedral symmetry * single stranded RNA * nucleocapsid contains the RNA and a single core protein * has an envelope (made of lipid bilayer) * 66% protein, 12% carbohydrate, 17% lipid * morphogenesis occurs at intracellular membranes, after replication the virions are transported to the cell surface and are released via exocytosis * viral infectivity is inactivated by heat (56 degrees for 30 minutes). Also by ultraviolet radiation and lipid detergents * small surface projections of envelope that make the envelope appear rough * it is an arbovirus, which is an RNA containing virus that is transmitted from animals to humans by insects * hosts = humans, monkeys * the virus replicates in a variety of cell cultures which include primary chick and duck embryos; human cells; hamster, rabbit and monkey kidney cell lines * the virus is studied by capturing mosquitoes; it is detected through virus, after, ae, rna, protein, mosquitoes, monkey, lipid, human, fever, envelope, cell, africa, aedes, yellow, symptoms, surface, south, single, prevalent, nucleocapsid, nausea, monkeys, humans, days, cells, blood, asia, areas, america, aegypti, aches, within, white, west