Creatine

Creatine Creatine Creatine is an amino acid derivative; it is also know as a-methylguanidino acetic acid. Chevreul, a French scientist, from a sample meat extract, discovered it in 1832. Creatine is derived from the Greek word Kreas, which means flesh. Typical creatine users take about 20 g/d as a “loading dose” and 5 g/d as a maintenance dose. An average 70 Kg adult stores about 120 g of creatine, turning over 2-3 g per day. A vast majority of total body creatine is stored in skeletal muscles, 60% of which is in the form of creatine phosphate. It’s produced in the body naturally, but most is acquired from dietary sources. The liver, pancreas, and kidneys synthesize 2% of the total body creatine. Creatine is synthesized by three different amino acids: arginine, glycine, and methionine. It is eliminated from the kidneys after its converted into creatinine. Creatine is a non-protein amino acid found in animals and plants but there are less in plants then animals. Creatine is synthesized in the kidney, liver and pancreas from the amino acids L-arginine, glycine and L-methionine. Following its biosynthesis, creatine is transported to the skeletal creatine, phosphate, monohydrate, supplement, taking, body, been, athletes, studies, means, make, effects, citrate, amino, water, term, take, popular, muscle, milligrams, kidney, effective, benefits, because, acid, about, creatine, types, toxicity, total, tissues, three, synthesized, supplements, supplementation